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The transcription factor involved in response to amino acid starvation is activating transcription factor 4 (ATF4), which binds to the CSE promoter in addition to promoters of other amino acid biosynthetic and transport genes (Harding et al ., 2003)
A study on glutathione supplementation in NAFLD patients reported significant reductions in ALT levels after 4 months of treatment, with early improvements detectable at the 4-8 week mark (Honda et al., 2017)
Sandhu Y, Harada N, Harada S, Nishimaki T, Sasano H, Tanabe Y, Takeshige T, Matsuno K, Ishimori A, Katsura Y, et al
